Silver assisted stereo-directed assembly of branched peptide nucleic acids

Silver assisted stereo-directed assembly of branched peptide nucleic acids

Isolation and Sequencing of Cu-, Fe-, and Zn-Binding Whey Peptides for Potential Neuroprotective Applications as Multitargeted Compounds 

This study aims to isolate metal-binding peptides and synthesize promising amino acid sequences to potentially act as neuroprotective compounds in the future, targeting different mechanisms. Fractions of whey metal-binding peptides (Cu, Fe, and Zn) isolated by immobilized metal affinity chromatography showed different amino acid profiles according to the metal.

The Cu-binding peptides presented roughly twofold increase in the in vitro antioxidant, as assessed by oxygen radical absorbance capacity and anticholinesterase activities over the hydrolysate. This is probably because of the higher concentration of aromatic and basic residues, the latter being crucial for binding to the anionic sites of acetylcholinesterase.

Six peptide sequences were synthesized based on the metal-binding sites, molecular mass, hydrophobicity, and bioactivity probability.

Among the synthetic peptides, the VF dipeptide stood out both for its in vitro antioxidant and anticholinesterase activities. This peptide, as well as the fraction of Cu-binding peptides, should be further studied because it may act through different mechanisms related to neurodegenerative diseases, in addition to the chelation of the excess of metals in the central nervous system.

Scorpion sting: N-terminal fragment of proB-type natriuretic peptide as an early predictor of pediatric cardiotoxicity 

Aim of the work: This prospective study was conducted to evaluate the clinical reliability of N-terminal fragment of proB-type natriuretic peptide (NT-proBNP) in identifying patients with cardiotoxicity in the early hours following scorpion sting.

Subjects and methods: This study involved 483 children aging between 2-17 years who were admitted to Minia University Poisoning Control Center from 1st January 2010 to 31st December 2019 with a history of scorpion sting, and on clinical evaluation symptoms were manifested. All subjects were clinically examined, investigated for NT-proBNP and CPK-MB on admission, 6 h and 24 h post-envenomation; and subjected to 24 h cardiac monitoring with periodic ECG every 6 h.

Results: Assessment of CPK-MB levels showed a significant increase in all moderate to severe cases 6 h post-envenomation. Assessment of NT-proBNP levels showed a significant increase in all moderate to severe cases on admission and 6 h post-envenomation. Moreover, there was a significant decrease in the NT-proBNP level after 24 h compared with that measured on admission. The sensitivity of NT-proBNP for the diagnosis of myocardial injury at hospital admission was significantly higher than that of CPK-MB.

 

Conclusion: NT-proBNP may be a valuable and sensitive laboratory biomarker to predict cardiotoxicity of scorpion sting in the early hours.

Investigating the role of chain and linker length on the catalytic activity of an H 2 production catalyst containing a β-hairpin peptide  

Building on our recent report of an active H2 production catalyst [Ni(PPh 2NProp-peptide)2]2+ (Prop = para-phenylpropionic acid, peptide (R10) = WIpPRWTGPR-NH2, p = D-proline and P2N = 1-aza-3,6-diphosphacycloheptane) that contains structured β-hairpin peptides, here we investigate how H2 production is effected by: (1) the length of the hairpin (eight or ten residues) and (2) limiting the flexibility between the peptide and the core complex by altering the length of the linker: para-phenylpropionic acid (three carbons) or para-benzoic acid (one carbon).

Reduction of the peptide chain length from ten to eight residues increases or maintains the catalytic current for H2 production for all complexes, suggesting a non-productive steric interaction at longer peptide lengths. While the structure of the hairpin appears largely intact for the complexes, NMR data are consistent with differences in dynamic behavior which may contribute to the observed differences in catalytic activity.

Molecular dynamics simulations demonstrate that complexes with a one-carbon linker have the desired effect of restricting the motion of the hairpin relative to the complex; however, the catalytic currents are significantly reduced compared to complexes containing a three-carbon linker as a result of the electron withdrawing nature of the -COOH group. These results demonstrate the complexity and interrelated nature of the outer coordination sphere on catalysis.

epitoolkit
epitoolkit

SV40 large T-antigen (RFP-Bsd), EF1a lentiviral particles
LVP557-RB 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing RFP-Blasticidin fusion dual marker.

SV40 large T-antigen (GFP-Puro), CMV lentiviral particles
LVP016-GP 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing GFP-puromycin fusion dual marker.

SV40 large T-antigen (RFP-Puro), CMV lentiviral particles
LVP016-RP 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing RFP-puromycin fusion dual marker.

SV40 large T-antigen (GFP-Puro), EF1a lentiviral particles
LVP557-GP 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing GFP-puromycin fusion dual marker.

SV40 large T-antigen (RFP-Puro), EF1a lentiviral particles
LVP557-RP 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing RFP-puromycin fusion dual marker.

SV40 large T-antigen (Bsd) in PBS, CMV lentiviral particles
LVP016-Bsd-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing Blasticidin marker, provided in PBS solution.

SV40 large T-antigen (Neo) in PBS, CMV lentiviral particles
LVP016-Neo-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing Neomycin marker, provided in PBS solution.

SV40 large T-antigen (Bsd) in PBS, EF1a lentiviral particles
LVP557-Bsd-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing Blasticidin marker, provided in PBS solution.

SV40 large T-antigen (Neo) in PBS, EF1a lentiviral particles
LVP557-Neo-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing Neomycin marker, provided in PBS solution.

SV40 large T-antigen (Puro) in PBS, CMV lentiviral particles
LVP016-Puro-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing puromycin marker, provided in PBS solution.

SV40 T Antigen antibody
10R-2451 250 uL
EUR 550.8
Description: Mouse monoclonal SV40 Large T Antigen antibody

SV40 T Antigen antibody
10R-S122a 100 ug
EUR 950.4
Description: Mouse monoclonal SV40 T Antigen antibody

SV40 T Antigen antibody
10R-S128a 200 ug
EUR 950.4
Description: Mouse monoclonal SV40 T Antigen antibody

SV40 large T-antigen (Puro) in PBS, EF1a lentiviral particles
LVP557-Puro-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing puromycin marker, provided in PBS solution.

Large T Antigen (LT) Protein
20-abx654150
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Large T Antigen (LT) Antibody
20-abx177313
  • EUR 1479.60
  • EUR 710.40
  • 1 mg
  • 200 ug

SV40 large T-antigen (GFP-Bsd) in PBS, CMV lentiviral particles
LVP557-GB-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing GFP-Blasticidin fusion dual marker, provided in PBS solution.

SV40 large T-antigen (GFP-Bsd) in PBS, CMV lentiviral particles
LVP016-GB-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing GFP-Blasticidin fusion dual marker, provided in PBS solution.

SV40 large T-antigen (RFP-Bsd) in PBS, CMV lentiviral particles
LVP016-RB-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing RFP-Blasticidin fusion dual marker, provided in PBS solution.

SV40 large T-antigen (RFP-Bsd) in PBS, EF1a lentiviral particles
LVP557-RB-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing RFP-Blasticidin fusion dual marker, provided in PBS solution.

SV40 large T-antigen (GFP-Puro) in PBS, CMV lentiviral particles
LVP016-GP-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing GFP-puromycin fusion dual marker, provided in PBS solution.

SV40 large T-antigen (RFP-Puro) in PBS, CMV lentiviral particles
LVP016-RP-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing RFP-puromycin fusion dual marker, provided in PBS solution.

SV40 large T-antigen (GFP-Puro) in PBS, EF1a lentiviral particles
LVP557-GP-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing GFP-puromycin fusion dual marker, provided in PBS solution.

SV40 large T-antigen (RFP-Puro) in PBS, EF1a lentiviral particles
LVP557-RP-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing RFP-puromycin fusion dual marker, provided in PBS solution.

SV40 T Antigen Rabbit mAb
E2R27328 100ul
EUR 255
Description: Available in various conjugation types.

SV40 T Antigen Cell Immortalization Kit
CILV01 1 Kit
EUR 1094.8

Large T antigen - rhesus polyomavirus 560-568
A1078-1 1 mg
EUR 129.6
Description: Large T antigen - rhesus polyomavirus 560-568 has a peptide sequence of Ser-Glu-Phe-Leu-Leu-Glu-Lys-Arg-Ile.T antigen is required for viral DNA replication, transcription, and virion assembly.

Large T antigen - rhesus polyomavirus 560-568
A1078-10 10 mg
EUR 408
Description: Large T antigen - rhesus polyomavirus 560-568 has a peptide sequence of Ser-Glu-Phe-Leu-Leu-Glu-Lys-Arg-Ile.T antigen is required for viral DNA replication, transcription, and virion assembly.

Large T antigen - rhesus polyomavirus 560-568
A1078-25 25 mg
EUR 547.2
Description: Large T antigen - rhesus polyomavirus 560-568 has a peptide sequence of Ser-Glu-Phe-Leu-Leu-Glu-Lys-Arg-Ile.T antigen is required for viral DNA replication, transcription, and virion assembly.

Large T antigen - rhesus polyomavirus 560-568
A1078-5 5 mg
EUR 268.8
Description: Large T antigen - rhesus polyomavirus 560-568 has a peptide sequence of Ser-Glu-Phe-Leu-Leu-Glu-Lys-Arg-Ile.T antigen is required for viral DNA replication, transcription, and virion assembly.

T, Pallidum recombinant antigen p15
00141-V-01mg 0,1 mg
EUR 321
Description: T. Pallidum recombinant antigen p15 (full length)

T, Pallidum recombinant antigen p15
00141-V-1000ug 1000 ug
EUR 1539
Description: T. Pallidum recombinant antigen p15 (full length)

T, Pallidum recombinant antigen p17
00142-V-01mg 0,1 mg
EUR 321
Description: T. Pallidum recombinant antigen p17 (full length)

T, Pallidum recombinant antigen p17
00142-V-1000ug 1000 ug
EUR 1539
Description: T. Pallidum recombinant antigen p17 (full length)

T, Pallidum recombinant antigen p45
00143-V-01mg 0,1 mg
EUR 321
Description: T. Pallidum recombinant antigen p45 (full length)

T, Pallidum recombinant antigen p45
00143-V-1000ug 1000 ug
EUR 1539
Description: T. Pallidum recombinant antigen p45 (full length)

LARGE Recombinant Protein (Rat)
RP207821 100 ug Ask for price

T, pallidum recombinant antigen TmpA
00144-V-01mg 0,1 mg
EUR 321
Description: T. Pallidum recombinant antigen TmpA (full length)

T, pallidum recombinant antigen TmpA
00144-V-1000ug 1000 ug
EUR 1539
Description: T. Pallidum recombinant antigen TmpA (full length)

LARGE Recombinant Protein (Mouse)
RP146864 100 ug Ask for price

LARGE Recombinant Protein (Human)
RP040651 100 ug Ask for price

Recombinant Like Glycosyltransferase (LARGE)
4-RPH936Hu01
  • EUR 560.83
  • EUR 273.60
  • EUR 1773.12
  • EUR 671.04
  • EUR 1222.08
  • EUR 451.20
  • EUR 4252.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Like Glycosyltransferase expressed in: E.coli

Recombinant MeV Large Polymerase Protein
VAng-Lsx0385-inquire inquire Ask for price
Description: Recombinant MeV Large Polymerase containing the large polymerase immunodominant regions, 58-149 amino acids was expressed in E. coli and purified by proprietary chromatographic technique.

Recombinant Discs, Large Homolog 3 (DLG3)
4-RPG764Hu01
  • EUR 588.79
  • EUR 280.80
  • EUR 1877.95
  • EUR 705.98
  • EUR 1291.97
  • EUR 469.20
  • EUR 4514.88
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Discs, Large Homolog 3 expressed in: E.coli

Recombinant Discs, Large Homolog 5 (DLG5)
4-RPD069Hu01
  • EUR 507.07
  • EUR 259.20
  • EUR 1571.52
  • EUR 603.84
  • EUR 1087.68
  • EUR 415.20
  • EUR 3748.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Discs, Large Homolog 5 expressed in: E.coli

Recombinant Discs, Large Homolog 5 (DLG5)
4-RPD069Mu01
  • EUR 539.33
  • EUR 267.60
  • EUR 1692.48
  • EUR 644.16
  • EUR 1168.32
  • EUR 436.80
  • EUR 4051.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Discs, Large Homolog 5 expressed in: E.coli

Recombinant human Disks large homolog 5
P2339 100ug Ask for price
Description: Recombinant protein for human Disks large homolog 5

T. Pallidum recombinant antigen p15 (full length)
00141-V-100ugvial 100 ug/vial
EUR 150
Description: T. Pallidum recombinant antigen p15 (full length)

T. Pallidum recombinant antigen p17 (full length)
00142-V-100ugvial 100 ug/vial
EUR 150
Description: T. Pallidum recombinant antigen p17 (full length)

T. Pallidum recombinant antigen p45 (full length)
00143-V-100ugvial 100 ug/vial
EUR 150
Description: T. Pallidum recombinant antigen p45 (full length)

Recombinant Calpain 2, Large Subunit (CAPN2)
4-RPC358Hu01
  • EUR 571.58
  • EUR 276.00
  • EUR 1813.44
  • EUR 684.48
  • EUR 1248.96
  • EUR 458.40
  • EUR 4353.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Calpain 2, Large Subunit expressed in: E.coli

Recombinant Calpain 1, Large Subunit (CAPN1)
4-RPB964Hu01
  • EUR 642.55
  • EUR 295.20
  • EUR 2079.55
  • EUR 773.18
  • EUR 1426.37
  • EUR 505.20
  • EUR 5018.88
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Calpain 1, Large Subunit expressed in: E.coli

Recombinant Calpain 1, Large Subunit (CAPN1)
4-RPB964Hu02
  • EUR 642.55
  • EUR 295.20
  • EUR 2079.55
  • EUR 773.18
  • EUR 1426.37
  • EUR 505.20
  • EUR 5018.88
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Calpain 1, Large Subunit expressed in: E.coli

Recombinant Calpain 1, Large Subunit (CAPN1)
4-RPB964Mu01
  • EUR 657.60
  • EUR 300.00
  • EUR 2136.00
  • EUR 792.00
  • EUR 1464.00
  • EUR 516.00
  • EUR 5160.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Calpain 1, Large Subunit expressed in: E.coli

Recombinant Calpain 1, Large Subunit (CAPN1)
4-RPB964Mu02
  • EUR 657.60
  • EUR 300.00
  • EUR 2136.00
  • EUR 792.00
  • EUR 1464.00
  • EUR 516.00
  • EUR 5160.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Calpain 1, Large Subunit expressed in: E.coli

Recombinant Calpain 1, Large Subunit (CAPN1)
4-RPB964Ra01
  • EUR 668.35
  • EUR 302.40
  • EUR 2176.32
  • EUR 805.44
  • EUR 1490.88
  • EUR 523.20
  • EUR 5260.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Calpain 1, Large Subunit expressed in: E.coli

Recombinant Calpain 1, Large Subunit (CAPN1)
4-RPB964Ra02
  • EUR 668.35
  • EUR 302.40
  • EUR 2176.32
  • EUR 805.44
  • EUR 1490.88
  • EUR 523.20
  • EUR 5260.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Calpain 1, Large Subunit expressed in: E.coli

T. Pallidum recombinant antigen TmpA (full length)
00144-V-100ugvial 100 ug/vial
EUR 150
Description: T. Pallidum recombinant antigen TmpA (full length)

Recombinant human T-lymphocyte activation antigen CD80
P2350 100ug Ask for price
Description: Recombinant protein for human T-lymphocyte activation antigen CD80

Measles Virus Large Polymerase (58-149) (Recombinant)
22060553-1 100 µg
EUR 264.47

Measles Virus Large Polymerase (2059-2183) (Recombinant)
22060555-1 100 µg
EUR 264.47

B-Cell Lymphoma Extra Large Human (Recombinant)
22060807-1 2 µg
EUR 137.27

Recombinant Measles Virus Large Polymerase (58-149)
7-07837 100µg Ask for price

Recombinant Measles Virus Large Polymerase (58-149)
7-07838 500µg Ask for price

Recombinant Measles Virus Large Polymerase (58-149)
7-07839 1000µg Ask for price

Recombinant Measles Virus Large Polymerase (2059-2183)
7-07843 100µg Ask for price

Recombinant Measles Virus Large Polymerase (2059-2183)
7-07844 500µg Ask for price

Recombinant Measles Virus Large Polymerase (2059-2183)
7-07845 1000µg Ask for price

Recombinant Human Disks Large Homolog 4 Protein
RP01106 10 μg
EUR 228

Recombinant Large Multifunctional Peptidase 2 (LMP2)
4-RPA329Hu01
  • EUR 459.77
  • EUR 246.00
  • EUR 1394.11
  • EUR 544.70
  • EUR 969.41
  • EUR 382.80
  • EUR 3305.28
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Large Multifunctional Peptidase 2 expressed in: E.coli

Recombinant Large Multifunctional Peptidase 2 (LMP2)
4-RPA329Mu01
  • EUR 599.54
  • EUR 283.20
  • EUR 1918.27
  • EUR 719.42
  • EUR 1318.85
  • EUR 476.40
  • EUR 4615.68
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Large Multifunctional Peptidase 2 expressed in: E.coli

Recombinant Large Multifunctional Peptidase 7 (LMP7)
4-RPB556Hu01
  • EUR 605.99
  • EUR 285.60
  • EUR 1942.46
  • EUR 727.49
  • EUR 1334.98
  • EUR 481.20
  • EUR 4676.16
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Large Multifunctional Peptidase 7 expressed in: E.coli

Recombinant Large Multifunctional Peptidase 7 (LMP7)
4-RPB556Mu01
  • EUR 636.10
  • EUR 294.00
  • EUR 2055.36
  • EUR 765.12
  • EUR 1410.24
  • EUR 501.60
  • EUR 4958.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Large Multifunctional Peptidase 7 expressed in: E.coli

Recombinant Large Multifunctional Peptidase 7 (LMP7)
4-RPB556Ra01
  • EUR 679.10
  • EUR 304.80
  • EUR 2216.64
  • EUR 818.88
  • EUR 1517.76
  • EUR 530.40
  • EUR 5361.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Large Multifunctional Peptidase 7 expressed in: E.coli

Recombinant human Large subunit GTPase 1 homolog
P2203 100ug Ask for price
Description: Recombinant protein for human Large subunit GTPase 1 homolog

Recombinant Human Cytotoxic T-Lymphocyte Associated Antigen-4
7-00253 5µg Ask for price

Recombinant Human Cytotoxic T-Lymphocyte Associated Antigen-4
7-00254 25µg Ask for price

Recombinant Human Cytotoxic T-Lymphocyte Associated Antigen-4
7-00255 1mg Ask for price

Human Cytotoxic T-Lymphocyte Associated Antigen-4 (Recombinant)
22060046-1 10 µg
EUR 146.42

B-Cell Lymphoma Extra Large Human (Recombinant) , GST
22060817-1 2 µg
EUR 137.27

Recombinant human Disks large-associated protein 2
P2762 100ug Ask for price
Description: Recombinant protein for human Disks large-associated protein 2

AFP Antigen (Recombinant)）
E62C00202 20ug
EUR 458.4

NSE Antigen (Recombinant)
E62C00301 20ug
EUR 458.4

NSE Antigen (Recombinant)
E62C00302 20ug
EUR 411.6

Recombinant (E.Coli) Measles Virus Large Polymerase (58-149)
RP-651 100 ug
EUR 343.2

Recombinant (E.Coli) Measles Virus Large Polymerase (2059-2183)
RP-653 100 ug
EUR 343.2

HBV surface recombinant antigen HBsAg antigen
00123-V-01mg 0,1 mg
EUR 321
Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant High purity

HBV surface recombinant antigen HBsAg antigen
00123-V-1000ug 1000 ug
EUR 1539
Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant High purity

HBV surface recombinant antigen HBsAg antigen
00124-V-01mg 0,1 mg
EUR 321
Description: HBV surface recombinant antigen HBsAg antigen 31 kDa E. coli recombinant

HBV surface recombinant antigen HBsAg antigen
00124-V-1000ug 1000 ug
EUR 1539
Description: HBV surface recombinant antigen HBsAg antigen 31 kDa E. coli recombinant

Recombinant Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)
4-RPB230Hu01
  • EUR 567.29
  • EUR 274.80
  • EUR 1797.31
  • EUR 679.10
  • EUR 1238.21
  • EUR 454.80
  • EUR 4313.28
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Cytotoxic T-Lymphocyte Associated Antigen 4 expressed in: E.coli

Recombinant Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)
4-RPB230Mu01
  • EUR 593.09
  • EUR 282.00
  • EUR 1894.08
  • EUR 711.36
  • EUR 1302.72
  • EUR 472.80
  • EUR 4555.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Cytotoxic T-Lymphocyte Associated Antigen 4 expressed in: E.coli

Recombinant Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)
4-RPB230Ra01
  • EUR 599.54
  • EUR 283.20
  • EUR 1918.27
  • EUR 719.42
  • EUR 1318.85
  • EUR 476.40
  • EUR 4615.68
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Cytotoxic T-Lymphocyte Associated Antigen 4 expressed in: E.coli

HBV surface recombinant antigen HBsAg antigen 31 kDa E. coli recombinant
00124-V-100ugvial 100 ug/vial
EUR 150
Description: HBV surface recombinant antigen HBsAg antigen 31 kDa E. coli recombinant

Recombinant human Isoform 3 of Disks large homolog 3
P1864 100ug Ask for price
Description: Recombinant protein for human Isoform 3 of Disks large homolog 3

Recombinant human Isoform 3 of Disks large homolog 4
P1865 100ug Ask for price
Description: Recombinant protein for human Isoform 3 of Disks large homolog 4

B-Cell Lymphoma Extra Large Human (Recombinant) , His Tag
22060808-1 2 µg
EUR 137.27

Recombinant mouse U2 snRNP auxiliary factor large subunit
P2599 100ug Ask for price
Description: Recombinant protein for mouse U2 snRNP auxiliary factor large subunit

Recombinant Human Disks Large Homolog 4 Protein, His Tag
E40KMP1755 20ug
EUR 495

Recombinant MeV Active Large Polymerase Protein (aa 58-149)
VAng-Lsx0397-inquire inquire Ask for price
Description: Measles Active Large Polymerase protein (aa 58-149), recombinant protein from E. coli.

Recombinant MeV Active Large Polymerase Protein (aa 2059-2183)
VAng-Lsx0399-inquire inquire Ask for price
Description: Measles Active Large Polymerase protein (aa 2059-2183), recombinant protein from E. coli.

Recombinant Helicobacter Pylori Urease, Large Subunit Protein
VAng-Lsx3201-1mgEcoli 1 mg (E. coli)
EUR 4594.8
Description: Helicobacter Pylori Urease, Large Subunit, recombinant protein from E. coli.

Recombinant Helicobacter Pylori Urease, Large Subunit Protein
VAng-Lsx3201-500gEcoli 500 µg (E. coli)
EUR 3121.2
Description: Helicobacter Pylori Urease, Large Subunit, recombinant protein from E. coli.

Recombinant Helicobacter Pylori Urease, Large Subunit Protein
VAng-Lsx3201-50gEcoli 50 µg (E. coli)
EUR 2124
Description: Helicobacter Pylori Urease, Large Subunit, recombinant protein from E. coli.

Recombinant Syphilis antigen
E41H096 100ug
EUR 160

Recombinant Syphilis antigen
E41H097 100ug
EUR 160

Myoglobin antigen (Recombinant)
E64C00402 100ug
EUR 528

Recombinant Anaplamsa Antigen
E41H072 100ug
EUR 695

VZV gE recombinant antigen
00200-V-01mg 0,1 mg
EUR 321
Description: VZV gE recombinant antigen a.a. 48-135.

VZV gE recombinant antigen
00200-V-1000ug 1000 ug
EUR 1539
Description: VZV gE recombinant antigen a.a. 48-135.

Recombinant S Antigen (SAG)
4-RPB911Hu01
  • EUR 582.34
  • EUR 279.60
  • EUR 1853.76
  • EUR 697.92
  • EUR 1275.84
  • EUR 465.60
  • EUR 4454.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human S Antigen expressed in: E.coli

Recombinant S Antigen (SAG)
4-RPB911Mu01
  • EUR 593.09
  • EUR 282.00
  • EUR 1894.08
  • EUR 711.36
  • EUR 1302.72
  • EUR 472.80
  • EUR 4555.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse S Antigen expressed in: E.coli

HDV Ag recombinant antigen
00167-V-100ugvial 100ug/vial
EUR 150
Description: HDV Ag recombinant antigen

HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant
00122-V-100ugvial 100 ug/vial
EUR 150
Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant

Recombinant Leptospira Antigen
E41H058 100ug
EUR 395

Recombinant Leishmania Antigen
E41H070 100ug
EUR 695

Recombinant Leishmania Antigen
E41H071 100ug
EUR 695

Recombinant Toxoplasma Antigen
E41H083 100ug
EUR 695

HCV NS3 recombinant antigen
00117-V-01mg 0,1 mg
EUR 321
Description: HCV NS3 recombinant antigen a.a 1400 to a.a 1643 of HCV polyprotein 22 kDa

HCV NS3 recombinant antigen
00117-V-1000ug 1000 ug
EUR 1539
Description: HCV NS3 recombinant antigen a.a 1400 to a.a 1643 of HCV polyprotein 22 kDa

HAV P3C recombinant antigen
00162-V-01mg 0,1 mg
EUR 321
Description: HAV P3C recombinant antigen a.a. 1643-1743.

HAV P3C recombinant antigen
00162-V-1000ug 1000 ug
EUR 1539
Description: HAV P3C recombinant antigen a.a. 1643-1743.

HAV VP3 recombinant antigen
00163-V-01mg 0,1 mg
EUR 321
Description: HAV VP3 recombinant antigen a.a. 304-415.

HAV VP3 recombinant antigen
00163-V-1000ug 1000 ug
EUR 1539
Description: HAV VP3 recombinant antigen a.a. 304-415.

HCV core recombinant antigen
00115-V-01mg 0,1 mg
EUR 321
Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa

HCV core recombinant antigen
00115-V-1000ug 1000 ug
EUR 1539
Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa

HBV core recombinant antigen
00120-V-01mg 0,1 mg
EUR 321
Description: HBV core recombinant antigen HBcAg a.a 1 to a.a 183 of HBV core antigen 18 kDa

HBV core recombinant antigen
00120-V-1000ug 1000 ug
EUR 1539
Description: HBV core recombinant antigen HBcAg a.a 1 to a.a 183 of HBV core antigen 18 kDa

HCV core recombinant antigen
00152-V-01mg 0,1 mg
EUR 321
Description: HCV core recombinant antigen a.a.105-302

HCV core recombinant antigen
00152-V-1000ug 1000 ug
EUR 1539
Description: HCV core recombinant antigen a.a.105-302

VZV ORF9 recombinant antigen
00201-V-01mg 0,1 mg
EUR 321
Description: VZV ORF9 recombinant antigen a.a. 6-28/76-100.

VZV ORF9 recombinant antigen
00201-V-1000ug 1000 ug
EUR 1539
Description: VZV ORF9 recombinant antigen a.a. 6-28/76-100.

Recombinant HBV Core Antigen
VAng-Wyb8585-inquire inquire Ask for price
Description: Hepatitis B Core Antigen (HBcAg), recombinant protein from E. coli.

Recombinant HCV Core Antigen
VAng-Lsx04584-1mg 1 mg
EUR 2023.2
Description: Hepatitis C Virus Core Antigen, recombinant protein from E. coli.

Giardia Trophozoite Recombinant antigen antigen 34 kDa
00321-V-01mg 0,1 mg
EUR 321
Description: Giardia Trophozoite Recombinant antigen antigen 34 kDa a.a. 21-280

Giardia Trophozoite Recombinant antigen antigen 34 kDa
00321-V-1000ug 1000 ug
EUR 1539
Description: Giardia Trophozoite Recombinant antigen antigen 34 kDa a.a. 21-280

CMV Pp150 recombinant antigen
00186-V-01mg 0,1 mg
EUR 321
Description: CMV Pp150 recombinant antigen a.a. 426-606

CMV Pp150 recombinant antigen
00186-V-1000ug 1000 ug
EUR 1539
Description: CMV Pp150 recombinant antigen a.a. 426-606

VZV ORF26 recombinant antigen
00202-V-01mg 0,1 mg
EUR 321
Description: VZV ORF26 recombinant antigen a.a. 9-33/184-208.

VZV ORF26 recombinant antigen
00202-V-1000ug 1000 ug
EUR 1539
Description: VZV ORF26 recombinant antigen a.a. 9-33/184-208.

Recombinant human RHD antigen 
P1958 100ug Ask for price
Description: Recombinant protein for human RHD antigen 

Recombinant Human Disks Large Homolog 4/DLG4/PSD95 (N-6His)
CH23-10ug 10ug
EUR 187.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Disks Large Homolog 4/DLG4/PSD95 (N-6His)
CH23-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Disks Large Homolog 4/DLG4/PSD95 (N-6His)
CH23-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Disks Large Homolog 4/DLG4/PSD95 (N-6His)
CH23-50ug 50ug
EUR 442.8
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant (E.Coli) purified Measles virus Large Polymerase (2059-2183)
RP-1612 100 ug
EUR 416.4

Recombinant (E.Coli) purified Measles virus Large Polymerase (58-149)
RP-1613 100 ug
EUR 416.4

Recombinant Rat Disks large homolog 3 Protein, GST, E.coli-1mg
QP7691-ec-1mg 1mg
EUR 2763.6

SV40 T-antigen Rabbit Polyclonal Antibody
E12-872 100ug/100ul
EUR 255
Description: Available in various conjugation types.

Recombinant Rat Disks large homolog 3 Protein, GST, E.coli-10ug
QP7691-ec-10ug 10ug
EUR 326.4

Recombinant Rat Disks large homolog 3 Protein, GST, E.coli-50ug
QP7691-ec-50ug 50ug
EUR 434.4

Recombinant HCV Multiple Antigen
VAng-Lsx0198-1mg 1 mg
EUR 3360
Description: HCV Multiple Antigen, recombinant protein from E. coli.

Recombinant Lyme Disease Antigen
E41H066 100ug
EUR 695

Recombinant Lyme Disease Antigen
E41H067 100ug
EUR 695

Recombinant HCV Chimeric Antigen
VAng-Lsx04582-1mg 1 mg
EUR 703.2
Description: Hepatitis C Virus Chimeric Antigen, recombinant protein from E. coli.

Recombinant Rat Disks large homolog 3 Protein, GST, E.coli-100ug
QP7691-ec-100ug 100ug
EUR 685.2

Recombinant Rat Disks large homolog 3 Protein, GST, E.coli-200ug
QP7691-ec-200ug 200ug
EUR 1077.6

Recombinant Rat Disks large homolog 3 Protein, GST, E.coli-500ug
QP7691-ec-500ug 500ug
EUR 1816.8

Recombinant Carcinoembryonic Antigen
VAng-Cr3880-1mg 1 mg
EUR 2188.8
Description: Recombinant Carcinoembryonic Antigen, Host/Source: Mammalian Cell Expression System. The purity is> 95% by SDS-PAGE.

Recombinant Cryptosporidiumn Antigen
E41H059 100ug
EUR 395

Recombinant HBV e Antigen (aa 1-160)
VAng-0502Lsx-inquire inquire Ask for price
Description: Hepatitis B e Antigen (HBeAg) with 10 amino acid pre-core sequence, recombinant protein from E. coli, MW 17 kDa, 0.73 mg/mL.

VZV gE recombinant antigen a.a. 48-135.
00200-V-100ugvial 100 ug/vial
EUR 150
Description: VZV gE recombinant antigen a.a. 48-135.

HSV-1 gD recombinant antigen
00181-V-01mg 0,1 mg
EUR 321
Description: HSV-1 gD recombinant antigen a.a. 266-394.

HSV-1 gD recombinant antigen
00181-V-1000ug 1000 ug
EUR 1539
Description: HSV-1 gD recombinant antigen a.a. 266-394.

HSV-2 gD recombinant antigen
00182-V-01mg 0,1 mg
EUR 321
Description: HSV-2 gD recombinant antigen a.a. 266-394.

HSV-2 gD recombinant antigen
00182-V-1000ug 1000 ug
EUR 1539
Description: HSV-2 gD recombinant antigen a.a. 266-394.

HSV-2 gD recombinant antigen
00183-V-01mg 0,1 mg
EUR 321
Description: HSV-2 gD recombinant antigen a.a. 525-578.

HSV-2 gD recombinant antigen
00183-V-1000ug 1000 ug
EUR 1539
Description: HSV-2 gD recombinant antigen a.a. 525-578.

HSV-1 gD recombinant antigen
00184-V-01mg 0,1 mg
EUR 321
Description: HSV-1 gD recombinant antigen a.a. 84-175.

HSV-1 gD recombinant antigen
00184-V-1000ug 1000 ug
EUR 1539
Description: HSV-1 gD recombinant antigen a.a. 84-175.

HHV-4 recombinant EA antigen
00213-V-01mg 0,1 mg
EUR 321
Description: HHV-4 recombinant EA antigen. Region: 306-390aa

HHV-4 recombinant EA antigen
00213-V-1000ug 1000 ug
EUR 1539
Description: HHV-4 recombinant EA antigen. Region: 306-390aa

HSV-2 gB recombinant antigen
1131-V-01mg 0,1 mg
EUR 321
Description: HSV-2 gB recombinant antigen

HSV-2 gB recombinant antigen
1131-V-1000ug 1000 ug
EUR 1539
Description: HSV-2 gB recombinant antigen

HSV-1 gD recombinant antigen
8912 100 ug
EUR 608.1
Description: This is HSV-1 gD recombinant antigen for ELISA,WB.

HSV-1 gG recombinant antigen
8950 100 ug
EUR 529.8
Description: This is HSV-1 gG recombinant antigen for ELISA,WB.

HSV-2 gG recombinant antigen
8951 100 ug
EUR 529.8
Description: This is HSV-2 gG recombinant antigen for ELISA,WB.

HSV-2 gB recombinant antigen
1131-V-100ugvial 100 ug/vial
EUR 150
Description: HSV-2 gB recombinant antigen

Syphilis TmpA recombinant antigen
9004 100 ug
EUR 418.87
Description: This is Syphilis TmpA recombinant antigen for ELISA,WB.

Cyfra211 Antigen (Recombinant) (CK19)
E62C00802 20ug
EUR 458.4

Recombinant Brucella BP26 Antigen
E41H002 100ug
EUR 395

HAV P3C recombinant antigen a.a. 1643-1743.
00162-V-100ugvial 100 ug/vial
EUR 150
Description: HAV P3C recombinant antigen a.a. 1643-1743.

HAV VP3 recombinant antigen a.a. 304-415.
00163-V-100ugvial 100 ug/vial
EUR 150
Description: HAV VP3 recombinant antigen a.a. 304-415.

HIV-1 tat recombinant antigen
00110-V-01mg 0,1 mg
EUR 321
Description: HIV-1 tat recombinant antigen full length 15 kDa

HIV-1 tat recombinant antigen
00110-V-1000ug 1000 ug
EUR 1539
Description: HIV-1 tat recombinant antigen full length 15 kDa

HIV-1 nef recombinant antigen
00112-V-01mg 0,1 mg
EUR 321
Description: HIV-1 nef recombinant antigen a.a 3 to a.a 190 of the HIV-1 nef region 20 kDa

HIV-1 nef recombinant antigen
00112-V-1000ug 1000 ug
EUR 1539
Description: HIV-1 nef recombinant antigen a.a 3 to a.a 190 of the HIV-1 nef region 20 kDa

HAV HAV P2C recombinant antigen
00165-V-01mg 0,1 mg
EUR 321
Description: HAV HAV P2C recombinant antigen a.a. 1121-1234.

HAV HAV P2C recombinant antigen
00165-V-1000ug 1000 ug
EUR 1539
Description: HAV HAV P2C recombinant antigen a.a. 1121-1234.

HIV-1 p24 recombinant antigen,
00174-V-01mg 0,1 mg
EUR 321
Description: HIV-1 p24 recombinant antigen.

Recent advances in seafood bioactive peptides and their potential for managing osteoporosis 

Marine biodiversity provides a range of diverse biological resources, including seafoods that are rich in protein and a well-balanced amino acid composition. Previous studies have shown that peptides can improve bone formation and/or inhibit bone resorption, suggesting the potential for seafood bioactive peptides (SBPs) in development of food and pharmaceuticals for management of osteoporosis.

In this review, we provided an up-to-date overview of the anti-osteoporosis activity of SBPs and describe their underlying molecular mechanisms. We focus on SBPs’ development, broadening the scope and depth of research, as well as strengthening in vivo and clinical research.

In vitro cell cultures and in vivo animal osteoporosis models have demonstrated the potential for seafood-derived SBPs, including fish, mollusks, crustaceans, seaweed and microalgae, in preventing osteoporosis.

These peptides may act by activating the signaling pathways, such as BMP/Smads, MAPK, OPG/RANKL/RANK, and NF-κB, which are associated with modulation bone health.

Silver assisted stereo-directed assembly of branched peptide nucleic acids into four-point nanostars

Branched chiral peptide nucleic acids br(4S/R)-PNA with three arms of PNA-C4 strands were constructed on a central chiral core of 4(R/S)-aminoproline as the branching center. The addition of Ag+ triggered the self-assembly of branched PNAs through the formation of C-Ag+-C metallo base pairing of the three PNA C4 arms leading to non-covalent dendrimers, whose architecture is directed by the C4(R/S)-stereocenter of core 4-aminoproline.

The 4S-aminoprolyl core enabled the precise formation of four-pointed nanostars that was not realised with 4R-aminoprolyl or acyclic, achiral aminoethyl glycyl PNA cores. The dendritic assembly of 4 pointed nanostars exhibited net chirality of base stacks in CD spectra, while the base stack assembly from br(4R)-PNA 2 was overall achiral.

The results demonstrate that the silver assisted, 4S-aminoproline core stereo selective chiral assembly of branched PNAs manifests into nanostar morphology. The chiral branched PNAs open new vistas in the supramolecular organization of nucleic acids.

Peptide-Modified Nanoparticles for Tumor Targeting and Molecular Imaging 

Nanoparticles hold great promise in tumor targeting and molecular imaging because they can co-deliver therapeutic drugs and imaging agents to the tumor site with a single entity. Nanoparticles modified with ligands against moieties overexpressed on tumor tissues have gained increasing attention due to their active targeting mechanisms.

Peptides are well suited for nanoparticle targeting modifications because they are small, easy to synthesize and typically non-immunogenic. Herein, we review the peptide-modified nanoparticles used for tumor targeting therapy and molecular imaging based on the classification of peptide-targeting ligands. The development of targeting peptides and nanoparticles will also be discussed.

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