Silver assisted stereo-directed assembly of branched peptide nucleic acids

Silver assisted stereo-directed assembly of branched peptide nucleic acids

Isolation and Sequencing of Cu-, Fe-, and Zn-Binding Whey Peptides for Potential Neuroprotective Applications as Multitargeted Compounds 

This study aims to isolate metal-binding peptides and synthesize promising amino acid sequences to potentially act as neuroprotective compounds in the future, targeting different mechanisms. Fractions of whey metal-binding peptides (Cu, Fe, and Zn) isolated by immobilized metal affinity chromatography showed different amino acid profiles according to the metal.

The Cu-binding peptides presented roughly twofold increase in the in vitro antioxidant, as assessed by oxygen radical absorbance capacity and anticholinesterase activities over the hydrolysate. This is probably because of the higher concentration of aromatic and basic residues, the latter being crucial for binding to the anionic sites of acetylcholinesterase.

Six peptide sequences were synthesized based on the metal-binding sites, molecular mass, hydrophobicity, and bioactivity probability.

Among the synthetic peptides, the VF dipeptide stood out both for its in vitro antioxidant and anticholinesterase activities. This peptide, as well as the fraction of Cu-binding peptides, should be further studied because it may act through different mechanisms related to neurodegenerative diseases, in addition to the chelation of the excess of metals in the central nervous system.

Scorpion sting: N-terminal fragment of proB-type natriuretic peptide as an early predictor of pediatric cardiotoxicity 

Aim of the work: This prospective study was conducted to evaluate the clinical reliability of N-terminal fragment of proB-type natriuretic peptide (NT-proBNP) in identifying patients with cardiotoxicity in the early hours following scorpion sting.

Subjects and methods: This study involved 483 children aging between 2-17 years who were admitted to Minia University Poisoning Control Center from 1st January 2010 to 31st December 2019 with a history of scorpion sting, and on clinical evaluation symptoms were manifested. All subjects were clinically examined, investigated for NT-proBNP and CPK-MB on admission, 6 h and 24 h post-envenomation; and subjected to 24 h cardiac monitoring with periodic ECG every 6 h.

Results: Assessment of CPK-MB levels showed a significant increase in all moderate to severe cases 6 h post-envenomation. Assessment of NT-proBNP levels showed a significant increase in all moderate to severe cases on admission and 6 h post-envenomation. Moreover, there was a significant decrease in the NT-proBNP level after 24 h compared with that measured on admission. The sensitivity of NT-proBNP for the diagnosis of myocardial injury at hospital admission was significantly higher than that of CPK-MB.

 

Conclusion: NT-proBNP may be a valuable and sensitive laboratory biomarker to predict cardiotoxicity of scorpion sting in the early hours.

Investigating the role of chain and linker length on the catalytic activity of an H 2 production catalyst containing a β-hairpin peptide  

Building on our recent report of an active H2 production catalyst [Ni(PPh 2NProp-peptide)2]2+ (Prop = para-phenylpropionic acid, peptide (R10) = WIpPRWTGPR-NH2, p = D-proline and P2N = 1-aza-3,6-diphosphacycloheptane) that contains structured β-hairpin peptides, here we investigate how H2 production is effected by: (1) the length of the hairpin (eight or ten residues) and (2) limiting the flexibility between the peptide and the core complex by altering the length of the linker: para-phenylpropionic acid (three carbons) or para-benzoic acid (one carbon).

Reduction of the peptide chain length from ten to eight residues increases or maintains the catalytic current for H2 production for all complexes, suggesting a non-productive steric interaction at longer peptide lengths. While the structure of the hairpin appears largely intact for the complexes, NMR data are consistent with differences in dynamic behavior which may contribute to the observed differences in catalytic activity.

Molecular dynamics simulations demonstrate that complexes with a one-carbon linker have the desired effect of restricting the motion of the hairpin relative to the complex; however, the catalytic currents are significantly reduced compared to complexes containing a three-carbon linker as a result of the electron withdrawing nature of the -COOH group. These results demonstrate the complexity and interrelated nature of the outer coordination sphere on catalysis.

epitoolkit
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Sv40 Large T Antigen Antibody

GWB-Q01357 0.1 ml Ask for price

SV40 large T antigen NLS acetate

TP1830L-10mg 10mg Ask for price
Description: SV40 large T antigen NLS acetate

SV40 large T antigen NLS acetate

TP1830L-1g 1g Ask for price
Description: SV40 large T antigen NLS acetate

SV40 large T antigen NLS acetate

TP1830L-1mg 1mg Ask for price
Description: SV40 large T antigen NLS acetate

SV40 large T antigen NLS acetate

TP1830L-50mg 50mg Ask for price
Description: SV40 large T antigen NLS acetate

SV40 large T antigen NLS acetate

TP1830L-5mg 5mg Ask for price
Description: SV40 large T antigen NLS acetate

SV40 large T antigen NLS acetate

MBS5789447-10mg 10(mg
EUR 520

SV40 large T antigen NLS acetate

MBS5789447-1mg 1(mg
EUR 160

SV40 large T antigen NLS acetate

MBS5789447-5mg 5(mg
EUR 335

SV40 Large Antigen

E5800-01 20μg
EUR 203.83
Description: The major regulatory protein of SV40 virus

SV40 Large Antigen

E5800-02 100μg
EUR 779.35
Description: The major regulatory protein of SV40 virus

Recombinant Large T antigen (large T), partial

MBS1174021-005mgBaculovirus 0.05mg(Baculovirus)
EUR 1225

Recombinant Large T antigen (large T), partial

MBS1174021-005mgEColi 0.05mg(E-Coli)
EUR 1005

Recombinant Large T antigen (large T), partial

MBS1174021-005mgYeast 0.05mg(Yeast)
EUR 1110

Recombinant Large T antigen (large T), partial

MBS1174021-02mgEColi 0.2mg(E-Coli)
EUR 1300

Recombinant Large T antigen (large T), partial

MBS1174021-05mgEColi 0.5mg(E-Coli)
EUR 1435

Recombinant Large T Antigen (LT)

RPU56223-100ug 100ug
EUR 649

Recombinant Large T Antigen (LT)

RPU56223-1mg 1mg
EUR 2558.4

Recombinant Large T Antigen (LT)

RPU56223-50ug 50ug
EUR 393.6

Recombinant Large T Antigen (LT)

RPB142Ge01 10ug
EUR 164

Recombinant Large T Antigen (LT)

RPB142Ge02 10ug
EUR 168

Recombinant Large T Antigen (LT)

RPB142Ge03 10ug
EUR 165

Recombinant Large T Antigen (LT)

MBS2122767-001mg 0.01mg
EUR 165

Recombinant Large T Antigen (LT)

MBS2122767-005mg 0.05mg
EUR 290

Recombinant Large T Antigen (LT)

MBS2122767-01mg 0.1mg
EUR 435

Recombinant Large T Antigen (LT)

MBS2122767-02mg 0.2mg
EUR 525

Recombinant Large T Antigen (LT)

MBS2122767-05mg 0.5mg
EUR 1005

Recombinant Large T Antigen (LT)

MBS2140122-001mg 0.01mg
EUR 170

Recombinant Large T Antigen (LT)

MBS2140122-005mg 0.05mg
EUR 295

Recombinant Large T Antigen (LT)

MBS2140122-01mg 0.1mg
EUR 445

Recombinant Large T Antigen (LT)

MBS2140122-02mg 0.2mg
EUR 540

Recombinant Large T Antigen (LT)

MBS2140122-05mg 0.5mg
EUR 1025

Recombinant Large T Antigen (LT)

MBS2140123-001mg 0.01mg
EUR 165

Recombinant Large T Antigen (LT)

MBS2140123-005mg 0.05mg
EUR 290

Recombinant Large T Antigen (LT)

MBS2140123-01mg 0.1mg
EUR 435

Recombinant Large T Antigen (LT)

MBS2140123-02mg 0.2mg
EUR 530

Recombinant Large T Antigen (LT)

MBS2140123-05mg 0.5mg
EUR 1005

Sv40 Large T-antigen (CMV, Zeo) Lentivirus

LVP016-Zeo 1x10^7 IFU/ml x 200ul
EUR 245
Description: Lentivirus expresses SV40 large T-antigen under suCMV promoter, containing Zeocin selection.

Sv40 Large T-antigen (EF1a, Zeo) Lentivirus

LVP557-Zeo 1x10^7 IFU/ml x 200ul
EUR 245
Description: Lentivirus expresses SV40 large T-antigen under EF1a promoter, containing Zeocin selection.

Sv40 Large T-antigen (CMV, Hygro) Lentivirus

LVP016-Hygro 1x10^7 IFU/ml x 200ul
EUR 245
Description: Lentivirus expresses SV40 large T-antigen under suCMV promoter, containing Hygromycin selection.

Recombinant BK polyomavirus Large T antigen, partial

MBS1167886-INQUIRE INQUIRE Ask for price

Recombinant WU polyomavirus Large T antigen, partial

MBS1113646-INQUIRE INQUIRE Ask for price

Recombinant JC polyomavirus Large T antigen, partial

MBS1087738-INQUIRE INQUIRE Ask for price

Recombinant KI polyomavirus Large T antigen, partial

MBS1058667-INQUIRE INQUIRE Ask for price

Recombinant BK polyomavirus Large T antigen, partial

MBS1262922-INQUIRE INQUIRE Ask for price

Sv40 Large T-antigen (EF1a, Hygro) Lentivirus

LVP557-Hygro 1x10^7 IFU/ml x 200ul
EUR 245
Description: Lentivirus expresses SV40 large T-antigen under EF1a promoter, containing Hygromycin selection.

Recombinant Murine polyomavirus Large T antigen, partial

MBS1159050-INQUIRE INQUIRE Ask for price

Recombinant Murine polyomavirus Large T antigen, partial

MBS1191454-INQUIRE INQUIRE Ask for price

Recombinant Bovine polyomavirus Large T antigen, partial

MBS1163701-INQUIRE INQUIRE Ask for price

Recombinant Murine polyomavirus Large T antigen, partial

MBS1058343-INQUIRE INQUIRE Ask for price

Recombinant Murine polyomavirus Large T antigen, partial

MBS1062525-INQUIRE INQUIRE Ask for price

Recombinant Hamster polyomavirus Large T antigen, partial

MBS1200765-INQUIRE INQUIRE Ask for price

Recombinant Simian virus 40 Large T antigen, partial

MBS1233967-INQUIRE INQUIRE Ask for price

Recombinant Simian virus 12 Large T antigen, partial

MBS1330600-INQUIRE INQUIRE Ask for price

SV40 Large T-antigen (CMV, no selection) lentivirus

LVP016 1x10^7 IFU/ml x 200ul
EUR 245
Description: lentiviral particles express SV40 large T-antigen under suCMV promoter, do not contain any selection marker.

SV40 large T-antigen (Bsd), CMV lentiviral particles

LVP016-Bsd 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing Blasticidin marker.

SV40 large T-antigen (Neo), CMV lentiviral particles

LVP016-Neo 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing Neomycin marker.

SV40 Large T-antigen (EF1a, no selection) lentivirus

LVP557 1x10^7 IFU/ml x 200ul
EUR 245
Description: lentiviral particles express SV40 large T-antigen under EF1a promoter, do not contain any selection marker.

SV40 large T-antigen (Bsd), EF1a lentiviral particles

LVP557-Bsd 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing Blasticidin marker.

SV40 large T-antigen (Neo), EF1a lentiviral particles

LVP557-Neo 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing Neomycin marker.

SV40 large T-antigen (Puro), CMV lentiviral particles

LVP016-Puro 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing puromycin marker.

SV40 large T-antigen (Puro), EF1a lentiviral particles

LVP557-Puro 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing puromycin marker.

Simian Virus 40 large T (SV40 large T) ELISA Kit

abx055954-100g 100 µg Ask for price

Simian Virus 40 large T (SV40 large T) ELISA Kit

abx055954-200g 200 µg Ask for price

Simian Virus 40 large T (SV40 large T) ELISA Kit

abx055954-50g 50 µg
EUR 493.75

Recombinant B-lymphotropic polyomavirus Large T antigen, partial

MBS1001968-INQUIRE INQUIRE Ask for price

Sv40 Large T-antigen (CMV, Zeo) Lentivirus in PBS

LVP016-Zeo-PBS 1x10^8 IFU/ml x 200ul
EUR 455
Description: concentrated Lentivirus expresses SV40 large T-antigen under suCMV promoter, containing Zeocin selection.

Sv40 Large T-antigen (EF1a, Zeo) Lentivirus in PBS

LVP557-Zeo-PBS 1x10^8 IFU/ml x 200ul
EUR 455
Description: concentrated Lentivirus expresses SV40 large T-antigen under EF1a promoter, containing Zeocin selection.

Sv40 Large T-antigen (CMV, Hygro) Lentivirus in PBS

LVP016-Hygro-PBS 1x10^8 IFU/ml x 200ul
EUR 455
Description: concentrated Lentivirus expresses SV40 large T-antigen under suCMV promoter, containing Hygromycin selection.

Sv40 Large T-antigen (EF1a, Hygro) Lentivirus in PBS

LVP557-Hygro-PBS 1x10^8 IFU/ml x 200ul
EUR 455
Description: concentrated Lentivirus expresses SV40 large T-antigen under EF1a promoter, containing Hygromycin selection.

SV40 T Antigen antibody

10R-S122a 100 ug
EUR 950.4
Description: Mouse monoclonal SV40 T Antigen antibody

SV40 T Antigen antibody

10R-S128a 200 ug
EUR 734
Description: Mouse monoclonal SV40 T Antigen antibody

SV40 T Antigen antibody

10R-2451 250 uL
EUR 550.8
Description: Mouse monoclonal SV40 Large T Antigen antibody

SV40 T Antigen antibody

MBS830423-INQUIRE INQUIRE Ask for price

SV40 T Antigen antibody

MBS531375-02mg 0.2mg
EUR 1130

SV40 T Antigen antibody

MBS531375-5x02mg 5x0.2mg
EUR 4935

Recombinant Budgerigar fledgling disease virus Large T antigen, partial

MBS1041716-INQUIRE INQUIRE Ask for price

SV40 large T-antigen (GFP-Bsd), CMV lentiviral particles

LVP557-GB 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing GFP-Blasticidin fusion dual marker.

SV40 large T-antigen (GFP-Bsd), CMV lentiviral particles

LVP016-GB 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing GFP-Blasticidin fusion dual marker.

SV40 large T-antigen (RFP-Bsd), CMV lentiviral particles

LVP016-RB 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing RFP-Blasticidin fusion dual marker.

SV40 large T-antigen (RFP-Bsd), EF1a lentiviral particles

LVP557-RB 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing RFP-Blasticidin fusion dual marker.

SV40 large T-antigen (GFP-Puro), CMV lentiviral particles

LVP016-GP 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing GFP-puromycin fusion dual marker.

SV40 large T-antigen (RFP-Puro), CMV lentiviral particles

LVP016-RP 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing RFP-puromycin fusion dual marker.

SV40 large T-antigen (GFP-Puro), EF1a lentiviral particles

LVP557-GP 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing GFP-puromycin fusion dual marker.

SV40 large T-antigen (RFP-Puro), EF1a lentiviral particles

LVP557-RP 1x107 IFU/ml x 200ul
EUR 418.8
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing RFP-puromycin fusion dual marker.

SV40 Large T-antigen (CMV, no selection) lentivirus in PBS

LVP016-PBS 1x10^8 IFU/ml x 200ul
EUR 455
Description: Concentrated lentivirus express SV40 large T-antigen under suCMV promoter, do not contain any selection marker, provided in PBS solution

Recombinant HDV Large delta antigen

CSB-MP313702HFN(A4) 7658 mg Ask for price

SV40 large T-antigen (Bsd) in PBS, CMV lentiviral particles

LVP016-Bsd-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing Blasticidin marker, provided in PBS solution.

SV40 large T-antigen (Neo) in PBS, CMV lentiviral particles

LVP016-Neo-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing Neomycin marker, provided in PBS solution.

SV40 Large T-antigen (EF1a, no selection) lentivirus in PBS

LVP557-PBS 1x10^8 IFU/ml x 200ul
EUR 455
Description: Concentrated lentivirus express SV40 large T-antigen under EF1a promoter, do not contain any selection marker, provided in PBS solution

SV40 large T-antigen (Bsd) in PBS, EF1a lentiviral particles

LVP557-Bsd-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing Blasticidin marker, provided in PBS solution.

SV40 large T-antigen (Neo) in PBS, EF1a lentiviral particles

LVP557-Neo-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing Neomycin marker, provided in PBS solution.

SV40 large T-antigen (Puro) in PBS, CMV lentiviral particles

LVP016-Puro-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing puromycin marker, provided in PBS solution.

SV40 large T-antigen (Puro) in PBS, EF1a lentiviral particles

LVP557-Puro-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing puromycin marker, provided in PBS solution.

SV40 T Antigen Rabbit mAb

E2R27328 100ul
EUR 255
Description: Available in various conjugation types.

SV40 T Antigen Rabbit mAb

57396 100ul
EUR 399

SV40 small T antigen, Antibody

GWB-AF327B 0.1 mg Ask for price

Mouse Anti-SV40 Large T Antigen Monoclonal antibody, clone I2

DMAB-CS23064 200 μg
EUR 720
Description: Mouse

SV40 large T-antigen (GFP-Bsd) in PBS, CMV lentiviral particles

LVP557-GB-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing GFP-Blasticidin fusion dual marker, provided in PBS solution.

SV40 large T-antigen (GFP-Bsd) in PBS, CMV lentiviral particles

LVP016-GB-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing GFP-Blasticidin fusion dual marker, provided in PBS solution.

SV40 large T-antigen (RFP-Bsd) in PBS, CMV lentiviral particles

LVP016-RB-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing RFP-Blasticidin fusion dual marker, provided in PBS solution.

SV40 large T-antigen (RFP-Bsd) in PBS, EF1a lentiviral particles

LVP557-RB-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing RFP-Blasticidin fusion dual marker, provided in PBS solution.

SV40 large T-antigen (GFP-Puro) in PBS, CMV lentiviral particles

LVP016-GP-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing GFP-puromycin fusion dual marker, provided in PBS solution.

SV40 large T-antigen (RFP-Puro) in PBS, CMV lentiviral particles

LVP016-RP-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under suCMV promoter, containing RFP-puromycin fusion dual marker, provided in PBS solution.

SV40 large T-antigen (GFP-Puro) in PBS, EF1a lentiviral particles

LVP557-GP-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing GFP-puromycin fusion dual marker, provided in PBS solution.

SV40 large T-antigen (RFP-Puro) in PBS, EF1a lentiviral particles

LVP557-RP-PBS 5x107 IFU/ml x 200ul
EUR 852
Description: Pre-made lentiviral particles expressing SV40 large T-antigen under EF1a promoter, containing RFP-puromycin fusion dual marker, provided in PBS solution.

SV40 T antigen (ab-1), Antibody

GWB-6116B9 0.2 mg Ask for price

SV40 T Antigen (Simian Virus 40)

MBS6508302-025mL 0.25mL
EUR 655

SV40 T Antigen (Simian Virus 40)

MBS6508302-5x025mL 5x0.25mL
EUR 2785

SV40 T Antigen Cell Immortalization Kit

CILV01 1 Kit
EUR 1094.8

SV40 T Antigen Rabbit Monoclonal Antibody

E10G22593 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Large T Antigen (LT) Protein

20-abx654150
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  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Large T Antigen (LT) Protein

abx654150-10g 10 µg
EUR 537.5

Large T Antigen (LT) Protein

abx654150-2g 2 µg
EUR 375

Large T Antigen (LT) Antibody

20-abx177313
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  • 1 mg
  • 200 ug

Large T Antigen (LT) Antibody

abx177313-96tests 96 tests
EUR 287.5

Echovirus Antigen, Recombinant

REC31776-100 0.1
EUR 276.84
Description: Proprietary recombinant antigen expressed in E. coli and purified by chromatography. Individually pooled antigens shown to react with QC serum panel (multiple negative, borderline and positive sera) within defined reactivity range in Coxsackie-/Echovirus

Echovirus Antigen, Recombinant

REC31776-500 0.5
EUR 1043.56
Description: Proprietary recombinant antigen expressed in E. coli and purified by chromatography. Individually pooled antigens shown to react with QC serum panel (multiple negative, borderline and positive sera) within defined reactivity range in Coxsackie-/Echovirus

Enterovirus Antigen, Recombinant

REC31772-100 0.1
EUR 276.84
Description: Proprietary recombinant antigen expressed in E. coli and purified by chromatography. Individually pooled antigens shown to react with QC serum panel (multiple negative, borderline and positive sera) within defined reactivity range in Coxsackie-/Echovirus IgA, IgG and IgM ELISA.

Enterovirus Antigen, Recombinant

REC31772-500 0.5
EUR 1043.56
Description: Proprietary recombinant antigen expressed in E. coli and purified by chromatography. Individually pooled antigens shown to react with QC serum panel (multiple negative, borderline and positive sera) within defined reactivity range in Coxsackie-/Echovirus IgA, IgG and IgM ELISA.

pLenti CMV/TO SV40 small + Large T (w612-1)

PVT38529 2ug
EUR 280

Helicobacter pylori urease large subunit antigen (RECOMBINANT)

HPA-5030-4 50ug
EUR 295

Helicobacter pylori urease large subunit antigen (RECOMBINANT)

HPA-5030-5 100ug
EUR 495

Helicobacter pylori Urease, Large Subunit Antigen, Recombinant

MBS635641-005mg 0.05mg
EUR 665

Helicobacter pylori Urease, Large Subunit Antigen, Recombinant

MBS635641-01mg 0.1mg
EUR 1000

Helicobacter pylori Urease, Large Subunit Antigen, Recombinant

MBS635641-5x01mg 5x0.1mg
EUR 4350

Ross River Virus Recombinant Antigen

REC31969-100 0.1
EUR 757.8
Description: Recombinant Ross River virus antigen expressed in HEK293 cells as virus-like particles and purified by sucrose density gradients and precipitation. Virus-like particles were then solubilized in PBS containing 0.2% SDS to prevent aggregation of particles. The preparation is not particulate. Antigens in the preparation include Envelope proteins 1 and 2 and Nucleoprotein.

Ross River Virus Recombinant Antigen

REC31969-500 0.5
EUR 2844.92
Description: Recombinant Ross River virus antigen expressed in HEK293 cells as virus-like particles and purified by sucrose density gradients and precipitation. Virus-like particles were then solubilized in PBS containing 0.2% SDS to prevent aggregation of particles. The preparation is not particulate. Antigens in the preparation include Envelope proteins 1 and 2 and Nucleoprotein.

Simain SV40 Antigen

MBS412623-5xHalfELISAPlatesEquivalent5x48Reactions 5xHalfELISAPlatesEquivalent(5x48Reactions)
EUR 1500

Large T Antigen (LT) Polyclonal Antibody

CAU31357-100ul 100ul
EUR 267.8

Large T Antigen (LT) Polyclonal Antibody

CAU31357-200ul 200ul
EUR 334.3

TSPyV Large T antigen Expression Lentivirus

LVP1385 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Lentivirus express Large T antigen of TSPyV (Trichodysplasia spinulosa-associated polyomavirus), containing RFP-Blasticidin dual selection.

MCPyV Large T antigen Expression Lentivirus

LVP1386 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Lentivirus express Large T antigen of MCPyV (Merkel cell polyomavirus), containing RFP-Blasticidin dual selection.

Recombinant Hepatitis delta virus genotype I Large delta antigen

CSB-YP313702HFN 6144 mg Ask for price

Recombinant Hepatitis delta virus genotype I Large delta antigen

AP78034 each Ask for price

Recombinant Hepatitis delta virus genotype I Large delta antigen

AP77311 each Ask for price

Recombinant Hepatitis delta virus genotype I Large delta antigen

CSB-BP313702HFN 140 mg Ask for price

Recombinant Hepatitis delta virus genotype I Large delta antigen

CSB-BP313702HFN(A4) 7409 mg Ask for price

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1213319-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1130

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1213319-002mgEColi 0.02mg(E-Coli)
EUR 715

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1213319-002mgYeast 0.02mg(Yeast)
EUR 880

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1213319-01mgEColi 0.1mg(E-Coli)
EUR 855

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1213319-01mgYeast 0.1mg(Yeast)
EUR 1035

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1161348-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1130

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1161348-002mgEColi 0.02mg(E-Coli)
EUR 715

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1161348-002mgYeast 0.02mg(Yeast)
EUR 880

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1161348-01mgEColi 0.1mg(E-Coli)
EUR 855

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1161348-01mgYeast 0.1mg(Yeast)
EUR 1035

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1181315-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1130

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1181315-002mgEColi 0.02mg(E-Coli)
EUR 715

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1181315-002mgYeast 0.02mg(Yeast)
EUR 880

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1181315-01mgEColi 0.1mg(E-Coli)
EUR 855

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1181315-01mgYeast 0.1mg(Yeast)
EUR 1035

Recombinant Hepatitis delta virus genotype II Large delta antigen

MBS1022287-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1130

Recombinant Hepatitis delta virus genotype II Large delta antigen

MBS1022287-002mgEColi 0.02mg(E-Coli)
EUR 715

Recombinant Hepatitis delta virus genotype II Large delta antigen

MBS1022287-002mgYeast 0.02mg(Yeast)
EUR 880

Recombinant Hepatitis delta virus genotype II Large delta antigen

MBS1022287-01mgEColi 0.1mg(E-Coli)
EUR 855

Recombinant Hepatitis delta virus genotype II Large delta antigen

MBS1022287-01mgYeast 0.1mg(Yeast)
EUR 1035

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1117117-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1130

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1117117-002mgEColi 0.02mg(E-Coli)
EUR 715

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1117117-002mgYeast 0.02mg(Yeast)
EUR 880

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1117117-01mgEColi 0.1mg(E-Coli)
EUR 855

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1117117-01mgYeast 0.1mg(Yeast)
EUR 1035

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1126282-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1130

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1126282-002mgEColi 0.02mg(E-Coli)
EUR 715

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1126282-002mgYeast 0.02mg(Yeast)
EUR 880

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1126282-01mgEColi 0.1mg(E-Coli)
EUR 855

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1126282-01mgYeast 0.1mg(Yeast)
EUR 1035

Recombinant Hepatitis delta virus genotype II Large delta antigen

MBS1129809-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1130

Recombinant Hepatitis delta virus genotype II Large delta antigen

MBS1129809-002mgEColi 0.02mg(E-Coli)
EUR 715

Recombinant Hepatitis delta virus genotype II Large delta antigen

MBS1129809-002mgYeast 0.02mg(Yeast)
EUR 880

Recombinant Hepatitis delta virus genotype II Large delta antigen

MBS1129809-01mgEColi 0.1mg(E-Coli)
EUR 855

Recombinant Hepatitis delta virus genotype II Large delta antigen

MBS1129809-01mgYeast 0.1mg(Yeast)
EUR 1035

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1156487-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1130

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1156487-002mgEColi 0.02mg(E-Coli)
EUR 715

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1156487-002mgYeast 0.02mg(Yeast)
EUR 880

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1156487-01mgEColi 0.1mg(E-Coli)
EUR 855

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1156487-01mgYeast 0.1mg(Yeast)
EUR 1035

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1082755-002mgBaculovirus 0.02mg(Baculovirus)
EUR 480

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1082755-002mgEColi 0.02mg(E-Coli)
EUR 710

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1082755-002mgYeast 0.02mg(Yeast)
EUR 420

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1082755-01mgEColi 0.1mg(E-Coli)
EUR 855

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1082755-01mgYeast 0.1mg(Yeast)
EUR 695

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1062832-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1130

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1062832-002mgEColi 0.02mg(E-Coli)
EUR 715

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1062832-002mgYeast 0.02mg(Yeast)
EUR 880

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1062832-01mgEColi 0.1mg(E-Coli)
EUR 855

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1062832-01mgYeast 0.1mg(Yeast)
EUR 1035

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1219996-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1130

Recombinant Hepatitis delta virus genotype I Large delta antigen

MBS1219996-002mgEColi 0.02mg(E-Coli)
EUR 715

Recent advances in seafood bioactive peptides and their potential for managing osteoporosis 

Marine biodiversity provides a range of diverse biological resources, including seafoods that are rich in protein and a well-balanced amino acid composition. Previous studies have shown that peptides can improve bone formation and/or inhibit bone resorption, suggesting the potential for seafood bioactive peptides (SBPs) in development of food and pharmaceuticals for management of osteoporosis.

In this review, we provided an up-to-date overview of the anti-osteoporosis activity of SBPs and describe their underlying molecular mechanisms. We focus on SBPs’ development, broadening the scope and depth of research, as well as strengthening in vivo and clinical research.

In vitro cell cultures and in vivo animal osteoporosis models have demonstrated the potential for seafood-derived SBPs, including fish, mollusks, crustaceans, seaweed and microalgae, in preventing osteoporosis.

These peptides may act by activating the signaling pathways, such as BMP/Smads, MAPK, OPG/RANKL/RANK, and NF-κB, which are associated with modulation bone health.

Silver assisted stereo-directed assembly of branched peptide nucleic acids into four-point nanostars

Branched chiral peptide nucleic acids br(4S/R)-PNA with three arms of PNA-C4 strands were constructed on a central chiral core of 4(R/S)-aminoproline as the branching center. The addition of Ag+ triggered the self-assembly of branched PNAs through the formation of C-Ag+-C metallo base pairing of the three PNA C4 arms leading to non-covalent dendrimers, whose architecture is directed by the C4(R/S)-stereocenter of core 4-aminoproline.

The 4S-aminoprolyl core enabled the precise formation of four-pointed nanostars that was not realised with 4R-aminoprolyl or acyclic, achiral aminoethyl glycyl PNA cores. The dendritic assembly of 4 pointed nanostars exhibited net chirality of base stacks in CD spectra, while the base stack assembly from br(4R)-PNA 2 was overall achiral.

The results demonstrate that the silver assisted, 4S-aminoproline core stereo selective chiral assembly of branched PNAs manifests into nanostar morphology. The chiral branched PNAs open new vistas in the supramolecular organization of nucleic acids.

Peptide-Modified Nanoparticles for Tumor Targeting and Molecular Imaging 

Nanoparticles hold great promise in tumor targeting and molecular imaging because they can co-deliver therapeutic drugs and imaging agents to the tumor site with a single entity. Nanoparticles modified with ligands against moieties overexpressed on tumor tissues have gained increasing attention due to their active targeting mechanisms.

Peptides are well suited for nanoparticle targeting modifications because they are small, easy to synthesize and typically non-immunogenic. Herein, we review the peptide-modified nanoparticles used for tumor targeting therapy and molecular imaging based on the classification of peptide-targeting ligands. The development of targeting peptides and nanoparticles will also be discussed.

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